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ADHD  |  Behavioral activation treatment |  Behavioral economics | Developmental science | Disparities research | Neuroimaging Nicotine Dependence |  Risk taking | Smoking cessation | Task Downloads



Difficulties with experiencing and regulating both negative affect and positive affect play a significant role in the development of problematic health behaviors like smoking. CAPER research on affective vulnerabilities and smoking spans the study of distress tolerance and negative reinforcement-based risk taking as mechanisms underlying smoking development and relapse among adolescent smokers, and developing and testing behavioral activation-based cessation interventions for adult and adolescent smokers with a focus on reward processing underlying treatment effects. These programs of research include novel basic laboratory and neuroimaging paradigms integrated with clinical outcomes in order to develop more targeted interventions.

Selected Grants

  1. Stage II Trial of Novel Behavioral Activation Intervention for Smoking Cessation.
  2. Distress Tolerance and Adolescent Smoking Cessation.


Selected Publications

  1. Myers, M.G., & MacPherson, L. (in press). Smoking and nicotine dependence in adolescence. In. Brown. S.A., Zucker, R.A. (Eds.).The Oxford Handbook of Adolescent Substance Abuse.
  2. Banducci, A., Long, K.E, & MacPherson, L. (in press). Case series of a Behavioral Activation –enhanced smoking cessation program for inpatient substance users with elevated depressive symptoms. Clinical Case Studies.
  3. MacPherson, L., Stipelman, B.A., Duplinsky, M., Brown, R.A., & Lejuez, C.W. (2008). Distress tolerance and pre-smoking treatment attrition: Examination of moderating relationships. Addictive Behaviors33, 1385-1393.
    → Click here for the article.
  4. MacPherson, L., Tull, M. T., Matusiewicz, A., Rodman, S., Strong, D.R., Kahler, C.W., Hopko, D., Zvolensky, M., Brown, R.B., & Lejuez, C.W. (2010). Randomized controlled trial of behavioral activation smoking cessation treatment for smokers with elevated depressive symptoms. Journal of Consulting and Clinical Psychology78, 55-61.
    → Click here for the article.